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Substitutions in the Eyelet Region Disrupt Cefepime Diffusion through the Escherichia coli OmpF Channel

The Escherichia coli OmpF porin is a nonspecific channel involved in the membrane translocation of small hydrophilic molecules and especially in the passage of β-lactam antibiotics. In order to understand the dynamic of charged-compound uptake through bacterial porins, specific charges located in th...

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Bibliografiska uppgifter
Huvudupphovsmän: Simonet, Valérie, Malléa, Monique, Pagès, Jean-Marie
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC89676/
https://ncbi.nlm.nih.gov/pubmed/10639355
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