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Substitutions in the Eyelet Region Disrupt Cefepime Diffusion through the Escherichia coli OmpF Channel
The Escherichia coli OmpF porin is a nonspecific channel involved in the membrane translocation of small hydrophilic molecules and especially in the passage of β-lactam antibiotics. In order to understand the dynamic of charged-compound uptake through bacterial porins, specific charges located in th...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
American Society for Microbiology
2000
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC89676/ https://ncbi.nlm.nih.gov/pubmed/10639355 |
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