In Vitro Activity of Riboflavin against the Human Malaria Parasite Plasmodium falciparum

The human malaria parasite Plasmodium falciparum digests hemoglobin and polymerizes the released free heme into hemozoin. This activity occurs in an acidic organelle called the food vacuole and is essential for survival of the parasite in erythrocytes. Since acidic conditions are known to enhance th...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Akompong, Thomas, Ghori, Nafisa, Haldar, Kasturi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10602728/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.1.88-96.2000
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