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Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1

A research program targeted toward the identification of expanded-spectrum nonnucleoside reverse transcriptase inhibitors which possess increased potency toward K103N-containing mutant human immunodeficiency virus (HIV) and which maintain pharmacokinetics consistent with once-a-day dosing has result...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Corbett, Jeffrey W., Ko, Soo S., Rodgers, James D., Jeffrey, Susan, Bacheler, Lee T., Klabe, Ronald M., Diamond, Sharon, Lai, Chii-Ming, Rabel, Shelley R., Saye, Jo Anne, Adams, Stephen P., Trainor, George L., Anderson, Paul S., Erickson-Viitanen, Susan K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10582878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.12.2893
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