Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1

A research program targeted toward the identification of expanded-spectrum nonnucleoside reverse transcriptase inhibitors which possess increased potency toward K103N-containing mutant human immunodeficiency virus (HIV) and which maintain pharmacokinetics consistent with once-a-day dosing has result...

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Main Authors: Corbett, Jeffrey W., Ko, Soo S., Rodgers, James D., Jeffrey, Susan, Bacheler, Lee T., Klabe, Ronald M., Diamond, Sharon, Lai, Chii-Ming, Rabel, Shelley R., Saye, Jo Anne, Adams, Stephen P., Trainor, George L., Anderson, Paul S., Erickson-Viitanen, Susan K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89583/
https://ncbi.nlm.nih.gov/pubmed/10582878
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