Association of Alterations in ParC and GyrA Proteins with Resistance of Clinical Isolates of Enterococcus faecium to Nine Different Fluoroquinolones

The parC and gyrA genes of 73 ciprofloxacin-resistant and 6 ciprofloxacin-susceptible Enterococcus faecium clinical isolates were partly sequenced. Alterations in ParC and GyrA, possibly in combination with other resistance mechanisms, severely restricted the in vitro activities of the nine quinolon...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Brisse, Sylvain, Fluit, Ad C., Wagner, Ulrich, Heisig, Peter, Milatovic, Dana, Verhoef, Jan, Scheuring, Sybille, Köhrer, Karl, Schmitz, Franz-Josef
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89510/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10508034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.10.2513
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