Association of Alterations in ParC and GyrA Proteins with Resistance of Clinical Isolates of Enterococcus faecium to Nine Different Fluoroquinolones

The parC and gyrA genes of 73 ciprofloxacin-resistant and 6 ciprofloxacin-susceptible Enterococcus faecium clinical isolates were partly sequenced. Alterations in ParC and GyrA, possibly in combination with other resistance mechanisms, severely restricted the in vitro activities of the nine quinolon...

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Bibliographische Detailangaben
Hauptverfasser: Brisse, Sylvain, Fluit, Ad C., Wagner, Ulrich, Heisig, Peter, Milatovic, Dana, Verhoef, Jan, Scheuring, Sybille, Köhrer, Karl, Schmitz, Franz-Josef
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89510/
https://ncbi.nlm.nih.gov/pubmed/10508034
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