Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii
The purine nucleoside analogue NBMPR {nitrobenzylthioinosine or 6-[(4-nitrobenzyl)thio]-9-β-d-ribofuranosylpurine} was selectively phosphorylated to its nucleoside 5′-monophosphate by Toxoplasma gondii but not mammalian adenosine kinase (EC 2.7.1.20). NBMPR was also cleaved in toxoplasma to its nucl...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1999
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10508021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.10.2437 |
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