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Quantitation of Intracellular Triphosphate of Emtricitabine in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Patients

An analytical methodology combining solid-phase extraction (SPE) and high-performance liquid chromatography (HPLC) was developed to quantitate the intracellular active 5′-triphosphate (TP) of β-l-2′,3′-dideoxy-5-fluoro-3′-thiacytidine (emtricitabine) (FTC) in human peripheral blood mononuclear cells...

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Detalhes bibliográficos
Main Authors: Darque, Albert, Valette, Gilles, Rousseau, Frank, Wang, Laurene H., Sommadossi, Jean-Pierre, Zhou, Xiao-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89455/
https://ncbi.nlm.nih.gov/pubmed/10471573
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