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Novel Expansions of the Gene Encoding Dihydropteroate Synthase in Trimethoprim-Sulfamethoxazole-Resistant Streptococcus pneumoniae

A study of eight sulfonamide-resistant clinical isolates of Streptococcus pneumoniae revealed chromosomal mutations within the gene encoding dihydropteroate synthase that play a role in conferring resistance to sulfamethoxazole. The presence of the suld mutation, found previously only in a laborator...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Padayachee, Thanugarani, Klugman, Keith P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89451/
https://ncbi.nlm.nih.gov/pubmed/10471569
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