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Evaluation of Low-Dose, Extended-Interval Clindamycin Regimens against Staphylococcus aureus and Streptococcus pneumoniae Using a Dynamic In Vitro Model of Infection

We have previously described the activity of low-dose clindamycin in extended-interval dosing regimens by determination of bactericidal titer in serum. In this study, we used a one-compartment in vitro dynamic infection model to compare the pharmacodynamics of clindamycin in three intravenous-dosing...

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Bibliografiska uppgifter
Huvudupphovsmän: Lewis, Russell E., Klepser, Michael E., Ernst, Erika J., Lund, Brian C., Biedenbach, Douglas J., Jones, Ronald N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC89405/
https://ncbi.nlm.nih.gov/pubmed/10428927
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