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Mefloquine Is Active In Vitro and In Vivo against Mycobacterium avium Complex

Despite the development of several agents, new classes of antimicrobials with activity against the Mycobacterium avium complex (MAC) are needed. Based on a broad screening of compounds, we found that mefloquine has MICs of 8 to 16 μg/ml by the BACTEC system and 16 μg/ml by broth microdilution for fi...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Bermudez, Luiz E., Kolonoski, Peter, Wu, Martin, Aralar, Priscilla A., Inderlied, Clark B., Young, Lowell S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89383/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.1870
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