Activities of Trovafloxacin Compared with Those of Other Fluoroquinolones against Purified Topoisomerases and gyrA and grlA Mutants of Staphylococcus aureus

Frequencies of mutation to resistance with trovafloxacin and four other quinolones were determined with quinolone-susceptible Staphylococcus aureus RN4220 by a direct plating method. First-step mutants were selected less frequently with trovafloxacin (1.1 × 10(−10) at 2 to 4× the MIC) than with levo...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gootz, Thomas D., Zaniewski, Richard P., Haskell, Suzanne L., Kaczmarek, Frank S., Maurice, Alison E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89379/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.1845
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!