Anti-Toxoplasma gondii Activities and Structure-Activity Relationships of Novel Fluoroquinolones Related to Trovafloxacin

Eleven novel fluoroquinolones closely related to trovafloxacin were evaluated for their in vitro activity against Toxoplasma gondii, and their structure-activity relationships were examined. The 50% inhibitory concentration (IC(50)) of trovafloxacin against T. gondii was 2.93 μM; the IC(50) of the 1...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Khan, Anis A., Araujo, Fausto G., Brighty, Katherine E., Gootz, Thomas D., Remington, Jack S.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Assuntos:	Susceptibility
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1783
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