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Anti-Toxoplasma gondii Activities and Structure-Activity Relationships of Novel Fluoroquinolones Related to Trovafloxacin

Eleven novel fluoroquinolones closely related to trovafloxacin were evaluated for their in vitro activity against Toxoplasma gondii, and their structure-activity relationships were examined. The 50% inhibitory concentration (IC(50)) of trovafloxacin against T. gondii was 2.93 μM; the IC(50) of the 1...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Khan, Anis A., Araujo, Fausto G., Brighty, Katherine E., Gootz, Thomas D., Remington, Jack S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 1999
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC89366/
https://ncbi.nlm.nih.gov/pubmed/10390245
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