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Biochemical-Genetic Analysis and Distribution of FAR-1, a Class A β-Lactamase from Nocardia farcinica

From genomic DNA of the clinical isolate Nocardia farcinica VIC, a 1.6-kb Sau3AI fragment was cloned and expressed in Escherichia coli JM109. The recombinant strain expressed a β-lactamase (pI, 4.6), FAR-1, which conferred high levels of resistance to amoxicillin, piperacillin, ticarcillin, and ceph...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Laurent, Frederic, Poirel, Laurent, Naas, Thierry, Chaibi, El Bachir, Labia, Roger, Boiron, Patrick, Nordmann, Patrice
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390216/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1644
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