Pharmacokinetic-Pharmacodynamic Contributions to the Convulsant Activity of Fluoroquinolones in Rats

The in vivo convulsant activities in rats of five representative fluoroquinolones (FQs), norfloxacin, enoxacin, sparfloxacin, fleroxacin, and pefloxacin, were compared. The experimental approach allowed distinction between the drugs’ ability to reach the pharmacological receptors at the level of the...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Delon, Annie, Bouquet, Serge, Huguet, Francois, Brunet, Valerie, Courtois, Philippe, Couet, William
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1999
Onderwerpen:	Pharmacology
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10348785/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.6.1511
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