In Vitro Activities of Antibiotics Alone and in Combination against Brucella melitensis at Neutral and Acidic pHs

Brucellae survive acidic pHs in phagolysosomes. Azithromycin, streptomycin, and quinolones were active against Brucella melitensis at pH 7.0 but not at pH 5.0; rifampin and doxycycline retained activity at pH 5.0. Regardless of pH, azithromycin-rifampin and ofloxacin-rifampin showed less synergy tha...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Akova, Murat, Gür, Deniz, Livermore, David M., Kocagöz, Tanil, Akalin, H. Erdal
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1999
Matèries:	Susceptibility
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1298
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