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Improved Derivatives of Bactenecin, a Cyclic Dodecameric Antimicrobial Cationic Peptide

Both linear and cyclic derivatives of the cyclic 12-amino-acid antimicrobial peptide bactenecin were designed based on optimization of amphipathicity and charge location. In general, increasing the number of positive charges at the N and C termini and adding an extra tryptophan residue in the loop n...

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Autori principali: Wu, Manhong, Hancock, Robert E. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC89258/
https://ncbi.nlm.nih.gov/pubmed/10223951
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