N-Acylated and d Enantiomer Derivatives of a Nonamer Core Peptide of Lactoferricin B Showing Improved Antimicrobial Activity

N-acylated or d enantiomer peptide derivatives based on the sequence RRWQWRMKK in lactoferricin B demonstrated antimicrobial activities greater than those of lactoferricin B against bacteria and fungi. The most potent peptide, conjugated with an 11-carbon-chain acyl group, showed two to eight times...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Wakabayashi, Hiroyuki, Matsumoto, Hiroshi, Hashimoto, Koichi, Teraguchi, Susumu, Takase, Mitsunori, Hayasawa, Hirotoshi
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Mechanisms of Action: Physiological Effects
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1267
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