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The Anti-Influenza Virus Drug Rimantadine Has Trypanocidal Activity
We report here that bloodstream forms of the African trypanosome, Trypanosoma brucei, are sensitive to the anti-influenza virus drug rimantadine (50% inhibitory concentration of 1.26 μg ml(−1) at pH 7.4). The activity is pH dependent and is consistent with a mechanism involving inhibition of the abi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC89245/ https://ncbi.nlm.nih.gov/pubmed/10103219 |
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