LY303366 Exhibits Rapid and Potent Fungicidal Activity in Flow Cytometric Assays of Yeast Viability

LY303366 is a semisynthetic analog of the antifungal lipopeptide echinocandin B that inhibits (1,3)-β-d-glucan synthase and exhibits efficacy in animal models of human fungal infections. In this study, we utilized flow cytometric analysis of propidium iodide uptake, single-cell sorting, and standard...

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Hlavní autoři: Green, Lisa J., Marder, Philip, Mann, Larry L., Chio, Li-Chun, Current, William L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89213/
https://ncbi.nlm.nih.gov/pubmed/10103187
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