Lactic Acid Polymers as Biodegradable Carriers of Fluoroquinolones: An In Vitro Study

A biodegradable polymer of dl-dilactide that facilitates release of ciprofloxacin or pefloxacin at levels exceeding MICs for the causative microorganisms of chronic osteomyelitis is described. Duration and peak of release were found to depend on the molecular weight of the polymer. Its characteristi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kanellakopoulou, Kyriaki, Kolia, Maria, Anastassiadis, Antonios, Korakis, Themistoklis, Giamarellos-Bourboulis, Evangelos J., Andreopoulos, Andreas, Dounis, Eleftherios, Giamarellou, Helen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049299/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.714
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