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Lactic Acid Polymers as Biodegradable Carriers of Fluoroquinolones: An In Vitro Study

A biodegradable polymer of dl-dilactide that facilitates release of ciprofloxacin or pefloxacin at levels exceeding MICs for the causative microorganisms of chronic osteomyelitis is described. Duration and peak of release were found to depend on the molecular weight of the polymer. Its characteristi...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Kanellakopoulou, Kyriaki, Kolia, Maria, Anastassiadis, Antonios, Korakis, Themistoklis, Giamarellos-Bourboulis, Evangelos J., Andreopoulos, Andreas, Dounis, Eleftherios, Giamarellou, Helen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049299/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.714
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