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Effectiveness and Toxicity of Gentamicin in an Experimental Model of Pyelonephritis: Effect of the Time of Administration

Temporal variations in the renal toxicity of aminoglycosides have been reported for experimental animals as well as for humans. In fact, maximal renal toxicity of aminoglycosides was observed when the drug was given during the rest period, while a lower toxicity was observed when the drug was inject...

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Detalhes bibliográficos
Main Authors: LeBrun, Michel, Grenier, Louis, Gourde, Pierrette, Bergeron, Michel G., Labrecque, Gaston, Beauchamp, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89106/
https://ncbi.nlm.nih.gov/pubmed/10223909
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