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Effectiveness and Toxicity of Gentamicin in an Experimental Model of Pyelonephritis: Effect of the Time of Administration

Temporal variations in the renal toxicity of aminoglycosides have been reported for experimental animals as well as for humans. In fact, maximal renal toxicity of aminoglycosides was observed when the drug was given during the rest period, while a lower toxicity was observed when the drug was inject...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: LeBrun, Michel, Grenier, Louis, Gourde, Pierrette, Bergeron, Michel G., Labrecque, Gaston, Beauchamp, Denis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89106/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1020
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