Effectiveness and Toxicity of Gentamicin in an Experimental Model of Pyelonephritis: Effect of the Time of Administration

Temporal variations in the renal toxicity of aminoglycosides have been reported for experimental animals as well as for humans. In fact, maximal renal toxicity of aminoglycosides was observed when the drug was given during the rest period, while a lower toxicity was observed when the drug was inject...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	LeBrun, Michel, Grenier, Louis, Gourde, Pierrette, Bergeron, Michel G., Labrecque, Gaston, Beauchamp, Denis
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Experimental Therapeutics
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1020
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