Comparison of a New Triazole Antifungal Agent, Schering 56592, with Itraconazole and Amphotericin B for Treatment of Histoplasmosis in Immunocompetent Mice

A murine model of intratracheally induced histoplasmosis was used to evaluate a new triazole antifungal agent, Schering (SCH) 56592, for treatment of histoplasmosis. MICs were determined for SCH 56592, amphotericin B, and itraconazole by testing yeast-phase isolates from 20 patients by a macrobroth...

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Hlavní autoři: Connolly, Patricia, Wheat, Joe, Schnizlein-Bick, Carol, Durkin, Michelle, Kohler, Steve, Smedema, Melinda, Goldberg, Janet, Brizendine, Edward, Loebenberg, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89071/
https://ncbi.nlm.nih.gov/pubmed/9925526
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