Comparison of a New Triazole Antifungal Agent, Schering 56592, with Itraconazole and Amphotericin B for Treatment of Histoplasmosis in Immunocompetent Mice

A murine model of intratracheally induced histoplasmosis was used to evaluate a new triazole antifungal agent, Schering (SCH) 56592, for treatment of histoplasmosis. MICs were determined for SCH 56592, amphotericin B, and itraconazole by testing yeast-phase isolates from 20 patients by a macrobroth...

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Main Authors: Connolly, Patricia, Wheat, Joe, Schnizlein-Bick, Carol, Durkin, Michelle, Kohler, Steve, Smedema, Melinda, Goldberg, Janet, Brizendine, Edward, Loebenberg, David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC89071/
https://ncbi.nlm.nih.gov/pubmed/9925526
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