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In Vitro Activity of the Ketolide HMR 3647 (RU 6647) for Legionella spp., Its Pharmacokinetics in Guinea Pigs, and Use of the Drug To Treat Guinea Pigs with Legionella pneumophila Pneumonia

The activities of HMR 3647, HMR 3004, erythromycin, clarithromycin, and levofloxacin for 97 Legionella spp. isolates were determined by microbroth dilution susceptibility testing. Growth inhibition of two Legionella pneumophila strains grown in guinea pig alveolar macrophages was also determined. Th...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Edelstein, Paul H., Edelstein, Martha A. C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.1.90
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