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Uptake and Intracellular Activity of Moxifloxacin in Human Neutrophils and Tissue-Cultured Epithelial Cells

The penetration by moxifloxacin of human neutrophils (polymorphonuclear leukocytes [PMN]) and tissue-cultured epithelial cells (McCoy cells) was evaluated by a fluorometric assay. At extracellular concentrations of 5 mg/liter, the cellular-to-extracellular concentration ratios (C/E) of moxifloxacin...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Pascual, Alvaro, García, Isabel, Ballesta, Sofía, Perea, Evelio J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.1.12
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