Uptake and Intracellular Activity of Moxifloxacin in Human Neutrophils and Tissue-Cultured Epithelial Cells

The penetration by moxifloxacin of human neutrophils (polymorphonuclear leukocytes [PMN]) and tissue-cultured epithelial cells (McCoy cells) was evaluated by a fluorometric assay. At extracellular concentrations of 5 mg/liter, the cellular-to-extracellular concentration ratios (C/E) of moxifloxacin...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Pascual, Alvaro, García, Isabel, Ballesta, Sofía, Perea, Evelio J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869557/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.1.12
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