Matrix Attachment Region-Dependent Function of the Immunoglobulin μ Enhancer Involves Histone Acetylation at a Distance without Changes in Enhancer Occupancy

Nuclear matrix attachment regions (MARs), which flank the immunoglobulin μ heavy-chain enhancer on either side, are required for the activation of the distal variable-region (V(H)) promoter in transgenic mice. Previously, we have shown that the MARs extend a local domain of chromatin accessibility a...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Fernández, Luis A., Winkler, Michael, Grosschedl, Rudolf
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2001
Materias:	Transcriptional Regulation
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11113195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.1.196-208.2001
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