Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2

Delta1, Jagged1, and Jagged2, commonly designated Delta/Serrate/LAG-2 (DSL) proteins, are known to be ligands for Notch1. However, it has been less understood whether they are ligands for Notch receptors other than Notch1. Meanwhile, ligand-induced cleavage and nuclear translocation of the Notch pro...

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Main Authors: Shimizu, Kiyoshi, Chiba, Shigeru, Hosoya, Noriko, Kumano, Keiki, Saito, Toshiki, Kurokawa, Mineo, Kanda, Yoshinobu, Hamada, Yoshio, Hirai, Hisamaru
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC88767/
https://ncbi.nlm.nih.gov/pubmed/10958687
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