Detection of Clarithromycin-Resistant Helicobacter pylori Strains by a Preferential Homoduplex Formation Assay

It has been shown that resistance to clarithromycin, a major cause of failure in Helicobacter pylori eradication therapy, is associated with point mutations in the 23S rRNA gene. We sought to apply the preferential homoduplex formation assay (PHFA), a novel technique for the efficient detection of p...

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Veröffentlicht in:	J Clin Microbiol
Hauptverfasser:	Maeda, Shin, Yoshida, Haruhiko, Matsunaga, Hironari, Ogura, Keiji, Kawamata, Osamu, Shiratori, Yasushi, Omata, Masao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Bacteriology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88697/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.38.1.210-214.2000
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