Detection of Clarithromycin-Resistant Helicobacter pylori Strains by a Preferential Homoduplex Formation Assay

It has been shown that resistance to clarithromycin, a major cause of failure in Helicobacter pylori eradication therapy, is associated with point mutations in the 23S rRNA gene. We sought to apply the preferential homoduplex formation assay (PHFA), a novel technique for the efficient detection of p...

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Библиографические подробности
Главные авторы: Maeda, Shin, Yoshida, Haruhiko, Matsunaga, Hironari, Ogura, Keiji, Kawamata, Osamu, Shiratori, Yasushi, Omata, Masao
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
Предметы:
Bacteriology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC88697/
https://ncbi.nlm.nih.gov/pubmed/10618089
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