Sequence Polymorphism in the rrs Gene of Mycobacterium tuberculosis Is Deeply Rooted within an Evolutionary Clade and Is Not Associated with Streptomycin Resistance

A mutation (C-to-T transition) at position 491 of the rrs gene was identified in a Mycobacterium tuberculosis strain family (n = 208 isolates) that was predominant in a suburb of Cape Town, South Africa. This nucleotide change is not involved in streptomycin resistance, and we suggest caution in ass...

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Hlavní autoři: Victor, Thomas C., van Rie, Annelies, Jordaan, Annemie M., Richardson, Madalene, van der Spuy, Gian D., Beyers, Nulda, van Helden, Paul D., Warren, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Mycobacteriology and Aerobic Actinomycetes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC88513/
https://ncbi.nlm.nih.gov/pubmed/11682556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.11.4184-4186.2001
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