Sequence Polymorphism in the rrs Gene of Mycobacterium tuberculosis Is Deeply Rooted within an Evolutionary Clade and Is Not Associated with Streptomycin Resistance

A mutation (C-to-T transition) at position 491 of the rrs gene was identified in a Mycobacterium tuberculosis strain family (n = 208 isolates) that was predominant in a suburb of Cape Town, South Africa. This nucleotide change is not involved in streptomycin resistance, and we suggest caution in ass...

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Detalles Bibliográficos

Publicado en:	J Clin Microbiol
Principais autores:	Victor, Thomas C., van Rie, Annelies, Jordaan, Annemie M., Richardson, Madalene, van der Spuy, Gian D., Beyers, Nulda, van Helden, Paul D., Warren, Robin
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Mycobacteriology and Aerobic Actinomycetes
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88513/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11682556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.39.11.4184-4186.2001
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