Detection of Rifampin Resistance in Mycobacterium tuberculosis in a Single Tube with Molecular Beacons

Current clinical assays for determining antibiotic susceptibility in Mycobacterium tuberculosis require many weeks to complete due to the slow growth of the bacilli. Here we demonstrate an extremely sensitive single-tube PCR assay that takes less than 3 h and reliably identifies rifampin-resistant M...

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Bibliographic Details
Main Authors: El-Hajj, Hiyam H., Marras, Salvatore A. E., Tyagi, Sanjay, Kramer, Fred Russell, Alland, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Bacteriology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC88498/
https://ncbi.nlm.nih.gov/pubmed/11682541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.11.4131-4137.2001
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