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Detection of Rifampin Resistance in Mycobacterium tuberculosis in a Single Tube with Molecular Beacons

Current clinical assays for determining antibiotic susceptibility in Mycobacterium tuberculosis require many weeks to complete due to the slow growth of the bacilli. Here we demonstrate an extremely sensitive single-tube PCR assay that takes less than 3 h and reliably identifies rifampin-resistant M...

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Detalhes bibliográficos
Main Authors: El-Hajj, Hiyam H., Marras, Salvatore A. E., Tyagi, Sanjay, Kramer, Fred Russell, Alland, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC88498/
https://ncbi.nlm.nih.gov/pubmed/11682541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.11.4131-4137.2001
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