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Epidemiologic Usefulness of Spoligotyping for Secondary Typing of Mycobacterium tuberculosis Isolates with Low Copy Numbers of IS6110

Restriction fragment length polymorphism (RFLP) analysis of IS6110 is commonly used to DNA fingerprint Mycobacterium tuberculosis. However, low-copy (≤5) IS6110 M. tuberculosis strains are poorly differentiated, requiring secondary typing. When spoligotyping was used as the secondary method, only 13...

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Bibliographic Details
Published in:J Clin Microbiol
Main Authors: Cronin, Wendy A., Golub, Jonathan E., Magder, Laurence S., Baruch, Nancy G., Lathan, Monica J., Mukasa, Leonard N., Hooper, Nancy, Razeq, Jafar H., Mulcahy, Donna, Benjamin, William H., Bishai, William R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88414/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.39.10.3709-3711.2001
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