Epidemiologic Usefulness of Spoligotyping for Secondary Typing of Mycobacterium tuberculosis Isolates with Low Copy Numbers of IS6110

Restriction fragment length polymorphism (RFLP) analysis of IS6110 is commonly used to DNA fingerprint Mycobacterium tuberculosis. However, low-copy (≤5) IS6110 M. tuberculosis strains are poorly differentiated, requiring secondary typing. When spoligotyping was used as the secondary method, only 13...

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Autors principals: Cronin, Wendy A., Golub, Jonathan E., Magder, Laurence S., Baruch, Nancy G., Lathan, Monica J., Mukasa, Leonard N., Hooper, Nancy, Razeq, Jafar H., Mulcahy, Donna, Benjamin, William H., Bishai, William R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC88414/
https://ncbi.nlm.nih.gov/pubmed/11574598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.10.3709-3711.2001
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