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Detection of rpoB Mutations in Mycobacterium tuberculosis by Biprobe Analysis

A biprobe assay utilizing LightCycler technology was developed to detect rifampin resistance-associated gene mutations in the Mycobacterium tuberculosis rpoB gene. Three biprobes detected all mutations present in the 46 rifampin-resistant isolates. Wild-type sequences were correctly identified in ea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Edwards, K. J., Metherell, L. A., Yates, M., Saunders, N. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC88343/
https://ncbi.nlm.nih.gov/pubmed/11526175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.9.3350-3352.2001
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