Detection of rpoB Mutations in Mycobacterium tuberculosis by Biprobe Analysis

A biprobe assay utilizing LightCycler technology was developed to detect rifampin resistance-associated gene mutations in the Mycobacterium tuberculosis rpoB gene. Three biprobes detected all mutations present in the 46 rifampin-resistant isolates. Wild-type sequences were correctly identified in ea...

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Bibliografiske detaljer

Udgivet i:	J Clin Microbiol
Principais autores:	Edwards, K. J., Metherell, L. A., Yates, M., Saunders, N. A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Mycobacteriology and Aerobic Actinomycetes
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11526175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.39.9.3350-3352.2001
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