Fluoroquinolone Resistance Is a Poor Surrogate Marker for Type II Topoisomerase Mutations in Clinical Isolates of Streptococcus pneumoniae

The association between fluoroquinolone susceptibility and DNA mutations coding for amino acid substitutions in the quinolone resistance-determining region was assessed with 44 clinical isolates of Streptococcus pneumoniae. Twenty-three strains bore at least one amino acid substitution. Only seven s...

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Pubblicato in:	J Clin Microbiol
Autori principali:	Millichap, John J., Pestova, Ekaterina, Siddiqui, Farida, Noskin, Gary A., Peterson, Lance R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Bacteriology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88221/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11427605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.39.7.2719-2721.2001
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