The Susceptibility of Mycobacterium tuberculosis to Isoniazid and the Arg→Leu Mutation at Codon 463 of katG Are Not Associated

A mutation (CCG→CTG [Arg→Leu]) in codon 463 of katG (catalase peroxidase) of Mycobacterium tuberculosis has been found in isoniazid (INH)-resistant strains. A PCR restriction endonuclease analysis to detect this mutation was applied to 395 M. tuberculosis isolates from patients in The Netherlands. T...

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Dades bibliogràfiques

Publicat a:	J Clin Microbiol
Autors principals:	van Doorn, H. R., Kuijper, E. J., van der Ende, A., Welten, A. G. A., van Soolingen, D., de Haas, P. E. W., Dankert, J.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Mycobacteriology and Aerobic Actinomycetes
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11283093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.39.4.1591-1594.2001
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