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Comparison of DNA Sequencing and a Line Probe Assay for Detection of Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Patients Failing Highly Active Antiretroviral Therapy

The resistance of human immunodeficiency virus type 1 (HIV-1) to drugs is a major cause of antiretroviral treatment failure. We have compared direct sequencing to a line probe assay (LiPA) for the detection of drug resistance-related mutations in 197 clinical samples, and we have investigated the se...

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Autors principals: Servais, Jean, Lambert, Christine, Fontaine, Elodie, Plesséria, Jean-Marc, Robert, Isabelle, Arendt, Vic, Staub, Thérèse, Schneider, François, Hemmer, Robert, Burtonboy, Guy, Schmit, Jean-Claude
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87758/
https://ncbi.nlm.nih.gov/pubmed/11158089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.2.454-459.2001
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