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Hepatitis C Virus Core Mutations Reduce the Sensitivity of a Fluorescence Enzyme Immunoassay

Four of 107 samples obtained from hepatitis C virus (HCV) carriers showed lower HCV core antigen levels in a fluorescence enzyme immunoassay (FEIA) than expected from corresponding HCV RNA levels. Nucleotide sequencing revealed a mutation in the HCV core region (Thr49Pro) that appears to have reduce...

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Sábháilte in:
Foilsithe in:J Clin Microbiol
Príomhchruthaitheoirí: Tokita, Hajime, Kaufmann, Gilbert R., Matsubayashi, Mamoru, Okuda, Isao, Tanaka, Tsukasa, Harada, Hideharu, Mukaide, Motokazu, Suzuki, Kazuo, Cooper, David A.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 2000
Ábhair:
Virology
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.38.9.3450-3452.2000
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