Hepatitis C Virus Core Mutations Reduce the Sensitivity of a Fluorescence Enzyme Immunoassay

Four of 107 samples obtained from hepatitis C virus (HCV) carriers showed lower HCV core antigen levels in a fluorescence enzyme immunoassay (FEIA) than expected from corresponding HCV RNA levels. Nucleotide sequencing revealed a mutation in the HCV core region (Thr49Pro) that appears to have reduce...

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Main Authors: Tokita, Hajime, Kaufmann, Gilbert R., Matsubayashi, Mamoru, Okuda, Isao, Tanaka, Tsukasa, Harada, Hideharu, Mukaide, Motokazu, Suzuki, Kazuo, Cooper, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Virology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87404/
https://ncbi.nlm.nih.gov/pubmed/10970401
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