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Identification of a Signal-Responsive Nuclear Export Sequence in Class II Histone Deacetylases

Activation of muscle-specific genes by the MEF2 transcription factor is inhibited by class II histone deacetylases (HDACs) 4 and 5, which contain carboxy-terminal deacetylase domains and amino-terminal extensions required for association with MEF2. The inhibitory action of HDACs is overcome by myoge...

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Udgivet i:Mol Cell Biol
Principais autores: McKinsey, Timothy A., Zhang, Chun Li, Olson, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11509672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.18.6312-6321.2001
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