Regulation of the Yeast Yap1p Nuclear Export Signal Is Mediated by Redox Signal-Induced Reversible Disulfide Bond Formation

Yap1p, a crucial transcription factor in the oxidative stress response of Saccharomyces cerevisiae, is transported in and out of the nucleus under nonstress conditions. The nuclear export step is specifically inhibited by H(2)O(2) or the thiol oxidant diamide, resulting in Yap1p nuclear accumulation...

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Dades bibliogràfiques
Autors principals: Kuge, Shusuke, Arita, Minetaro, Murayama, Asako, Maeta, Kazuhiro, Izawa, Shingo, Inoue, Yoshiharu, Nomoto, Akio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Nucleocytoplasmic Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87331/
https://ncbi.nlm.nih.gov/pubmed/11509657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6139-6150.2001
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